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Electroencephalographic evoked pain response is suppressed by spinal cord stimulation in complex regional pain syndrome: a case report

Hylands-White, N., Duarte, R. V., Beeson, P., Mayhew, S. D. and Raphael, J. H. (2016) Electroencephalographic evoked pain response is suppressed by spinal cord stimulation in complex regional pain syndrome: a case report. Journal of Clinical Monitoring and Computing. 30(6), pp. 845-848. 1387-1307.

Item Type: Article
Abstract: Pain is a subjective response that limits assessment. The purpose of this case report was to explore how the objectivity of the electroencephalographic response to thermal stimuli would be affected by concurrent spinal cord stimulation. A patient had been implanted with a spinal cord stimulator for the management of complex regional pain syndrome of both hands for 8 years. Following ethical approval and written informed consent we induced thermal stimuli using the Medoc PATHWAY Pain & Sensory Evaluation System on the right hand of the patient with the spinal cord stimulator switched off and with the spinal cord stimulator switched on. The patient reported a clinically significant reduction in thermal induced pain using the numerical rating scale (71.4 % reduction) with spinal cord stimulator switched on. Analysis of electroencephalogram recordings indicated the occurrence of contact heat evoked potentials (N2–P2) with spinal cord stimulator off, but not with spinal cord stimulator on. This case report suggests that thermal pain can be reduced in complex regional pain syndrome patients with the use of spinal cord stimulation and offers objective validation of the reported outcomes with this treatment.
Additional Information: A pre-publication version of this article was made available electronically by the publisher on 24 September 2015
Uncontrolled Keywords: Complex regional pain syndrome; contact heat evoked potentials; electroencephalography (EEG); spinal cord stimulation
Subjects: R Medicine > RB Pathology > RB127 Manifestations of disease > RB127.H355 Pain. Measurement
R Medicine > RM Therapeutics. Pharmacology > RM871 Electrotherapeutics
Creators: Hylands-White, Nicholas, Duarte, Rui V, Beeson, Paul, Mayhew, Stephen D and Raphael, Jon H
Publisher: Springer
Faculties, Divisions and Institutes: University Faculties, Divisions and Research Centres - OLD > Faculty of Health & Society
Date: 1 November 2016
Date Type: Publication
Page Range: pp. 845-848
Journal or Publication Title: Journal of Clinical Monitoring and Computing
Volume: 30
Number: 6
Language: English
DOI: https://doi.org/10.1007/s10877-015-9781-9
ISSN: 1387-1307
Status: Published / Disseminated
URI: http://nectar.northampton.ac.uk/id/eprint/7815

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