Allen, S. C. H. and Hebbes, T. R. (2003) Myb induced myeloid protein 1 (Mim-1) is an acetyltransferase. FEBS Letters. 534(1), pp. 119-124. 0014-5793.
| Item Type: | Article |
|---|---|
| Abstract: | We have screened protein extracts from chicken blood cells for acetyltransferases. An in gel acetyltransferase assay revealed that a 32 kDa protein, which is more prevalent in whole blood when compared with erythrocyte cells, possessed an auto-acetylation activity. This protein was purified by a series of chromatographic steps, sequenced by Edman degradation and subsequently identified as Myb induced myeloid protein (Mim-1). Mim-1 has similarities to the conserved acetyltransferase motifs found in the GNAT superfamily of proteins and also contains three minimal GK acetylation motifs. These data identify Mim-1 as an acetyltransferase |
| Uncontrolled Keywords: | Acetyltransferase, myeloid, erythroid, GNAT superfamily |
| Subjects: |
Q Science > QP Physiology > QP501 Animal biochemistry Q Science > QR Microbiology |
| Creators: | Allen, Stuart C H and Hebbes, Tim R |
| Publisher: | Elsevier |
| Faculties, Divisions and Institutes: |
University Faculties, Divisions and Research Centres - OLD > Faculty of Health & Society > Sports, Exercise & Life Sciences Faculties > Faculty of Health & Society > Sports, Exercise & Life Sciences |
| Date: | 16 January 2003 |
| Date Type: | Publication |
| Page Range: | pp. 119-124 |
| Journal or Publication Title: | FEBS Letters |
| Volume: | 534 |
| Number: | 1 |
| Language: | English |
| DOI: | https://doi.org/10.1016/S0014-5793(02)03803-6 |
| ISSN: | 0014-5793 |
| Status: | Published / Disseminated |
| URI: | http://nectar.northampton.ac.uk/id/eprint/5329 |
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