Marsden, G. L., Li, J., Everest, P. H., Lawson, A. J. and Ketley, J. M. (2009) Creation of a large deletion mutant in Campylobacter jejuni reveals the lipooligosaccharide gene cluster is not required for viability. Journal of Bacteriology. 191(7), pp. 2392-2399. 0021-9193.
Item Type: | Article |
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Abstract: | Deletion of the lipooligosaccharide biosynthesis region (Cj1132c to Cj1152c) from the genome of Campylobacter jejuni NCTC11168 shows that the core is not required for viability. The mutant was attenuated for growth and has increased sensitivity to antibiotics and detergents. Natural transformation and invasion of cultured host cells was abolished. |
Subjects: | Q Science > QR Microbiology > QR75 Bacteria |
Creators: | Marsden, Gemma L, Li, J, Everest, P H, Lawson, A J and Ketley, J M |
Publisher: | American Society for Microbiology |
Faculties, Divisions and Institutes: |
University Faculties, Divisions and Research Centres - OLD > Faculty of Health & Society > Sports, Exercise & Life Sciences Faculties > Faculty of Health & Society > Sports, Exercise & Life Sciences |
Date: | 30 January 2009 |
Date Type: | Publication |
Page Range: | pp. 2392-2399 |
Journal or Publication Title: | Journal of Bacteriology |
Volume: | 191 |
Number: | 7 |
Language: | English |
DOI: | https://doi.org/10.1128/JB.01397-08 |
ISSN: | 0021-9193 |
Status: | Published / Disseminated |
Refereed: | Yes |
URI: | http://nectar.northampton.ac.uk/id/eprint/3328 |
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