Off-licence prescribing and regulation in psychiatry: current challenges require a new model of governance

Sugarman, P., Mitchell, A., Frogley, C., Dickens, G. and Picchioni, M. (2013) Off-licence prescribing and regulation in psychiatry: current challenges require a new model of governance. Therapeutic Advances in Psychopharmacology. 3(4), pp. 233-243. 2045-1253.

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Item Type:	Article
Abstract:	The growing worldwide use of pharmaceuticals is managed in some countries by a regulatory system which sharply divides legal use into licensed and unlicensed categories. We examine how for the range of psychotropics this simultaneously restricts the possible benefits to patients, prescribers and producers in some domains, while failing to manage the risks in others. A more flexible system, which shares at an earlier stage experience and evidence on benefits and risks in patients, previously marginalized on the grounds of age, diagnosis or comorbidity, would aid the development of safer, more effective ‘real-world prescribing’. Practical recommendations are made for a new model of research and prescribing governance, to enable more effective repurposing of these treatments.
Uncontrolled Keywords:	Antidepressants, antipsychotics, off-label prescription, off-licence, mental health, pharmacotherapy, psychotropic medication, repurposing
Subjects:	R Medicine > RM Therapeutics. Pharmacology > RM138 Drug prescribing R Medicine > RC Internal medicine > RC435 Psychiatry
Creators:	Sugarman, Philip, Mitchell, Amy, Frogley, C, Dickens, Geoff and Picchioni, Marco
Publisher:	Sage
Northamptonshire and East Midlands:	Health
Faculties, Divisions and Institutes:	University Faculties, Divisions and Research Centres - OLD > Faculty of Health & Society > Mental Health and Learning Disability Faculties > Faculty of Health & Society > Nursing
Date:	August 2013
Date Type:	Publication
Page Range:	pp. 233-243
Journal or Publication Title:	Therapeutic Advances in Psychopharmacology
Volume:	3
Number:	4
Language:	English
DOI:	https://doi.org/10.1177/2045125312472530
ISSN:	2045-1253
Status:	Published / Disseminated
URI:	http://nectar.northampton.ac.uk/id/eprint/5557

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