Northampton Electronic Collection of Theses and Research

Myb induced myeloid protein 1 (Mim-1) is an acetyltransferase

Allen, S. C. H. and Hebbes, T. R. (2003) Myb induced myeloid protein 1 (Mim-1) is an acetyltransferase. FEBS Letters. 534(1), pp. 119-124. 0014-5793.

Item Type: Article
Abstract: We have screened protein extracts from chicken blood cells for acetyltransferases. An in gel acetyltransferase assay revealed that a 32 kDa protein, which is more prevalent in whole blood when compared with erythrocyte cells, possessed an auto-acetylation activity. This protein was purified by a series of chromatographic steps, sequenced by Edman degradation and subsequently identified as Myb induced myeloid protein (Mim-1). Mim-1 has similarities to the conserved acetyltransferase motifs found in the GNAT superfamily of proteins and also contains three minimal GK acetylation motifs. These data identify Mim-1 as an acetyltransferase
Uncontrolled Keywords: Acetyltransferase, myeloid, erythroid, GNAT superfamily
Subjects: Q Science > QP Physiology > QP501 Animal biochemistry
Q Science > QR Microbiology
Creators: Allen, Stuart C H and Hebbes, Tim R
Publisher: Elsevier
Faculties, Divisions and Institutes: University Faculties, Divisions and Research Centres - OLD > Faculty of Health & Society > Sports, Exercise & Life Sciences
Faculties > Faculty of Health & Society > Sports, Exercise & Life Sciences
Date: 16 January 2003
Date Type: Publication
Page Range: pp. 119-124
Journal or Publication Title: FEBS Letters
Volume: 534
Number: 1
Language: English
ISSN: 0014-5793
Status: Published / Disseminated

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