Northampton Electronic Collection of Theses and Research

Prevalence of organ-specific autoantibodies in childhood- and adult-onset type 1 diabetes

Allen, S., Huber, J. and Devendra, D. (2008) Prevalence of organ-specific autoantibodies in childhood- and adult-onset type 1 diabetes. Annals of the New York Academy of Sciences. 1150, pp. 260-262. 1749-6632.

Item Type: Article
Abstract: There are no studies that compare the prevalence of organ-specific autoantibodies (OSAs) between adult (>or= 16 years) and childhood-onset type 1 diabetes (T1D). We evaluated the prevalence of the following OSAs: thyroid peroxidase, thyroid receptor, parietal cell, intrinsic factor, tissue transglutaminase, adrenal cortex, mitochondrial, smooth muscle, liver kidney microsomal, and ovarian autoantibodies. Three hundred twenty-seven (327) adults were screened for one or more of these OSAs. The prevalence of all the OSAs studied was similar in both groups. The most prevalent OSA observed was tissue transglutaminase (childhood-onset disease = 14.3%; adult-onset disease = 13.6%). This study did not demonstrate a distinct difference in the prevalence of OSAs between adult- and childhood-onset T1D patients.
Uncontrolled Keywords: autoantibodies, type 1 diabetes, childhood, adult
Subjects: R Medicine > RC Internal medicine > RC660 Diabetes
Creators: Allen, S, Huber, Jorg and Devendra, D
Publisher: New York Academy of Sciences
Northamptonshire and East Midlands: Health
Faculties, Divisions and Institutes: University Faculties, Divisions and Research Centres - OLD > Faculty of Health & Society
Date: December 2008
Date Type: Publication
Page Range: pp. 260-262
Journal or Publication Title: Annals of the New York Academy of Sciences
Volume: 1150
Language: English
ISSN: 1749-6632
Status: Published / Disseminated

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