Northampton Electronic Collection of Theses and Research

Infected joint replacements in HIV-positive patients with haemophilia

Hicks, J. L., Ribbans, W. J., Buzzard, B., Kelley, S. S., Toft, L., Torri, G., Wiedel, J. D. and York, J. (2001) Infected joint replacements in HIV-positive patients with haemophilia. The Journal of Bone and Joint Surgery. 83(7), pp. 1050-1054. 1535-1386.

Item Type: Article
Abstract: Joint replacement in HIV-positive patients remains uncommon, with most experience gained in patients with haemophilia. We analysed retrospectively the outcome of 102 replacement arthroplasties in 73 HIV-positive patients from eight specialist haemophilia centres. Of these, 91 were primary procedures. The mean age of the patients at surgery was 39 years, and the median follow-up was for five years. The overall rate of deep sepsis was 18.7% for primary procedures and 36.3% for revisions. This is a much higher rate of infection than that seen in normal populations. A total of 44% of infections resolved fully after medical and/or surgical treatment. The benefits of arthroplasty in haemophilic patients are well established but the rates of complications are high. As this large study has demonstrated, high rates of infection occur, but survivorship analysis strongly suggests that most patients already diagnosed with HIV infection at the time of surgery should derive many years of symptomatic relief after a successful joint replacement. Careful counselling and education of both patients and healthcare workers before operation are therefore essential
Additional Information: UoA 12, RAE 2008
Subjects: R Medicine > RD Surgery > RD686 Arthroplasty
Creators: Hicks, J L, Ribbans, William J, Buzzard, B, Kelley, S S, Toft, L, Torri, G, Wiedel, J D and York, J
Faculties, Divisions and Institutes: University Faculties, Divisions and Research Centres - OLD > Faculty of Health & Society
Date: 1 September 2001
Date Type: Publication
Page Range: pp. 1050-1054
Journal or Publication Title: The Journal of Bone and Joint Surgery
Volume: 83
Number: 7
Language: English
ISSN: 1535-1386
Status: Published / Disseminated
Refereed: Yes
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