Using Bilateral and Unilateral Exercise to Better Understand the Blood Pressure Lowering Effects of Isometric Handgrip Training: Preliminary Findings

Pearl, M., Zokvic, M., Somani, Y., Badrov, M., Hanik, S.-A., Baross, A., Swaine, I. L., Milne, K. and McGowan, C. (2015) Using Bilateral and Unilateral Exercise to Better Understand the Blood Pressure Lowering Effects of Isometric Handgrip Training: Preliminary Findings. Other presented to: Canadian Society for Exercise Physiology, Hamalton, Canada, 2015-10-14 - 2019-03-17.

Baross_Anthony_APNM_2015_Using_Bilateral_and_Unilateral_Exercise_to_Better_Understand_the_Blood_Pressure_L ... (304kB)

Item Type:	Conference or Workshop Item (Other)
Abstract:	Isometric handgrip (IHG) training reduces resting blood pressure (BP) in normotensive individuals following 8-10 weeks of unilateral (4 x 2 minute sustained contractions at 30% maximal voluntary contraction (MVC) performed by the non-dominant limb, separated by 4 minutes rest) or bilateral IHG training (contractions alternating between dominant and non-dominant limb, separated by 1 minute rest), performed 3-5 times per week. Investigating the effects of a single bout of unilateral or bilateral IHG on vascular function (brachial artery flow-mediated dilation (FMD) and low-flow mediated constriction (L-FMC)) may provide insight into the underlying hypotensive mechanisms of IHG training. Eight young adult (25.3 ± 3.81 years), normotensive (99.65/61.25 ± 11.72/9.14 mmHg) women performed a single bout of bilateral (n=4) or unilateral (n=4) IHG exercise. FMD and L-FMC were assessed using ultrasound pre- and post-IHG bout. Following a single IHG bout, no significant changes were observed in FMD (unilateral: pre- = 13.56 ± 7.8%, post- =17.26 ± 21%, bilateral: pre- = 17.11 ± 1.1%, post- = 21.18 ± 8.9%) or L-FMC (unilateral: pre- = 3.36 ± 11%, post- =-2.26 ± 16%, bilateral: pre- = -2.86 ± 3.1%, post- = -1.94 ± 9.7%) in either group (all p > 0.05). Taken together these preliminary data suggest that in young healthy women, irrespective of isometric exercise on 1 or 2 limbs, the endothelium is not altered significantly. Further research with a larger sample is warranted to confirm that mechanisms other than improved vascular function play a role in IHG-training induced BP lowering.
Creators:	Pearl, M, Zokvic, M, Somani, Yasina, Badrov, M, Hanik, Sarah-Anne, Baross, Anthony, Swaine, Ian L, Milne, Kevin and McGowan, Cheri
Faculties, Divisions and Institutes:	Faculties > Faculty of Health & Society > Sports, Exercise & Life Sciences Research Centres > Centre for Physical Activity and Life Sciences
Date:	14 October 2015
Date Type:	Publication
Page Range:	p. 1
Journal or Publication Title:	Canadian Society for Exercise Physiology
Event Title:	Canadian Society for Exercise Physiology
Event Dates:	2015-10-14 - 2019-03-17
Place of Publication:	CAN
Event Location:	Hamalton, Canada
Event Type:	Other
Language:	English
Status:	Published / Disseminated
Refereed:	Yes
Related URLs:	https://pure.northampton.ac.uk/en/public...
URI:	http://nectar.northampton.ac.uk/id/eprint/12835

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