Allen, S. C. H. and Hebbes, T. R. (2003) Myb induced myeloid protein 1 (Mim-1) is an acetyltransferase. FEBS Letters. 534(1), pp. 119-124. 0014-5793.
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Abstract:
We have screened protein extracts from chicken blood cells for acetyltransferases. An in gel acetyltransferase assay revealed that a 32 kDa protein, which is more prevalent in whole blood when compared with erythrocyte cells, possessed an auto-acetylation activity. This protein was purified by a series of chromatographic steps, sequenced by Edman degradation and subsequently identified as Myb induced myeloid protein (Mim-1). Mim-1 has similarities to the conserved acetyltransferase motifs found in the GNAT superfamily of proteins and also contains three minimal GK acetylation motifs. These data identify Mim-1 as an acetyltransferase
Uncontrolled Keywords:
Acetyltransferase, myeloid, erythroid, GNAT superfamily
Subjects:
Creators:
Allen, S. C. H. and Hebbes, T. R.
Publisher:
Elsevier
Faculties, Divisions and Institutes:
Date:
16 January 2003
Date Type:
Publication
Page Range:
pp. 119-124
Journal or Publication Title:
FEBS Letters
Volume:
534
Number:
1
Language:
English
ISSN:
0014-5793
Status:
Published / Disseminated
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