Greenwood, S. A., Briggs, J., Walkin, C., Mangahis, E., Young, H., Castle, E., Billany, R., Asgari, E., Bhandari, S., Bishop, N., Bramham, K., Burton, J., Campbell, J., Chilcot, J., Cooper, N., Deelchand, V., Graham-Brown, M., Haggis, L., Hamilton, A., Jesky, M., Kalra, P., Koufaki, P., McCafferty, K., Nixon, A., Noble, H., Saynor, Z., Taal, M., Tollitt, J., Wheeler, D., Wilkinson, T., Worboys, H. and Macdonald, J. (2024) Kidney Beam - a cost-effective digital intervention to improve mental health. Kidney International Reports. 9(11), pp. 3204-3217. 2468-0249.
- Information
Information
Abstract:
There is inequity in provision of physical rehabilitation services for people living with chronic kidney disease (CKD). The Kidney BEAM trial evaluated the clinical value and cost effectiveness of a physical activity digital health intervention in CKD. In a single-blind, 11 centre, randomised controlled trial, 340 adult participants with CKD were randomly assigned to either the Kidney BEAM physical activity digital health intervention or a waitlist control. The primary outcomes were the difference in the Kidney Disease Quality of Life Short Form 1.3 Mental Component Summary (KDQoL-SF1.3 MCS) between intervention and control groups at 6 months, and cost-effectiveness. At 6 months there was a significant difference in mean adjusted change in KDQoL MCS score between Kidney BEAM and waitlist control (intention-to-treat adjusted mean: 5.9 {95% confidence interval: 4.4 to 7.5} arbitrary units, p<0.0001), and a 93% and 98% chance of the intervention being cost-effective at a willingness to pay threshold of £20,000 and £30,000 per quality-adjusted life year gained. In conclusion, the Kidney BEAM physical activity digital health intervention is a clinically valuable and cost-effective means to improve mental health related quality of life in people with CKD (trial registration no. NCT04872933).
Additional Information:
Authorship followed ICMJE guidelines. SAG, HY, REB, NB, JB, EMC, ZLS, HN, AH, KB, ACN, MPMG-B, TJW and JM were responsible for the inception and design of the project and prepared the manuscript. SAG, HY, REB, NB, JB, EMC, AH, VD, HN, ACN, TJW, JC, NC, HW, SB, JOB, PK, PAK, DCW, JT, MJ, MWT, EA, KM, ZLS, MPMG-B, and JM contributed to the design of the study, provided methodological input, and wrote the manuscript text and prepared Tables 1 to 3. All authors reviewed the manuscript.
Uncontrolled Keywords:
/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Creators:
Greenwood, S. A., Briggs, J., Walkin, C., Mangahis, E., Young, H., Castle, E., Billany, R., Asgari, E., Bhandari, S., Bishop, N., Bramham, K., Burton, J., Campbell, J., Chilcot, J., Cooper, N., Deelchand, V., Graham-Brown, M., Haggis, L., Hamilton, A., Jesky, M., Kalra, P., Koufaki, P., McCafferty, K., Nixon, A., Noble, H., Saynor, Z., Taal, M., Tollitt, J., Wheeler, D., Wilkinson, T., Worboys, H. and Macdonald, J.
Faculties, Divisions and Institutes:
?? HSRES ??
Date:
2 September 2024
Date Type:
Publication
Page Range:
pp. 3204-3217
Journal or Publication Title:
Kidney International Reports
Volume:
9
Number:
11
Number of Pages:
5396395
Language:
English
ISSN:
2468-0249
Status:
Published / Disseminated
Refereed:
Yes
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