Northampton Electronic Collection of Theses and Research

The role of vancomycin-soaking of the graft in anterior cruciate ligament reconstruction

Rodriguez-Merchan, E. C. and Ribbans, B. (2022) The role of vancomycin-soaking of the graft in anterior cruciate ligament reconstruction. Journal of ISAKOS. 7(2), pp. 94-98. 2059-7754.

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Rodriguez-Merchan_Ribbans_JISAKOS_2022_The_role_of_vancomycin-soaking_of_the_graft_in_anterior_cruciate_ligament_reconstruction
Rodriguez_Merchan_Ribbans_JISAKOS_2022_The_role_of_vancomycin_soaking_of_the_graft_in_anterior_cruciate_ligament_reconstruction.pdf - Published Version
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Abstract:
Approximately 1% of anterior cruciate ligament reconstruction (ACLR) procedures develop septic arthritis despite intravenous antibiotic prophylaxis and other preventive measures. Infection is most commonly due to contamination during autograft harvest and preparation by introducing bacteria into the knee during graft insertion. Pre-soaking ACL grafts in 5 mg/mL vancomycin ("vancomycin wrap") has been utilised to eradicate such bacterial contamination. Many level III studies have reported a marked decrease in infection rates with no increase in graft failure rates. However, the lack of prospective randomised control trials and these studies' heterogeneity do not allow a universal recommendation for vancomycin pre-soaking of all grafts during ACLR. Randomised controlled trials are needed to confirm efficacy in reducing sepsis rates. [Abstract copyright: Crown Copyright © 2022. Published by Elsevier Inc. All rights reserved.]
Uncontrolled Keywords:
Knee surgery, Anterior Cruciate Ligament, Sports Injuries, Antibiotics, Infection, Reconstruction, Post-operative infection, Autografts, Anterior Cruciate Ligament Reconstruction - methods, Humans, Pre-soaking ACL grafts, Anti-Bacterial Agents - pharmacology - therapeutic use, Anterior cruciate ligament, Anterior Cruciate Ligament Injuries - surgery, Vancomycin - therapeutic use, Graft
Creators:
Rodriguez-Merchan, E. C. and Ribbans, B.
Faculties, Divisions and Institutes:
?? ASSCI ??
Date:
1 April 2022
Date Type:
Publication
Page Range:
pp. 94-98
Journal or Publication Title:
Journal of ISAKOS
Volume:
7
Number:
2
Number of Pages:
5
Language:
English
DOI:
10.1016/j.jisako.2021.12.006
ISSN:
2059-7754
Status:
Published / Disseminated
Refereed:
Yes
Related URLs:
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