High-mobility group protein 1 (HMGB1) is an independent predictor of poor survival in ovarian cancer

Machado, L., Moseley, P., Moss, R., Nolan, C., Rampage, J., Chan, S. and Durrant, L. G. (2014) High-mobility group protein 1 (HMGB1) is an independent predictor of poor survival in ovarian cancer. Poster presented to: National Cancer Research Institute (NCRI) Cancer Conference, Liverpool, UK, 02-05 November 2014. Also presented at: British Society for Immunology Annual Congress (BSI2014), Brighton, UK, 01-04 December 2014 (Unpublished)

Information

[A][B][+][-]

Information

Abstract:

HMGB1 is a nuclear factor and a secreted damage associated molecular pattern (DAMP) that has a range of functions depending on its subcellular and extracellular localisation, redox state, and interaction with other cell surface receptors. HMGB1 has been implicated in numerous tumour types where expression levels may regulate tumour cell growth and survival as well as altering inflammatory cell recruitment to the tumour.

Subjects:

R Medicine > RC Internal medicine > RC254 Neoplasms. Tumors. Oncology

Creators:

Machado, L., Moseley, P., Moss, R., Nolan, C., Rampage, J., Chan, S. and Durrant, L. G.

Northamptonshire and East Midlands:

Health

Faculties, Divisions and Institutes:

University Faculties, Divisions and Research Centres - OLD > Faculty of Health & Society > Sports, Exercise & Life Sciences
University Faculties, Divisions and Research Centres - OLD > Research Centre > Institute of Health and Wellbeing > Ageing Research Centre
Faculties > Faculty of Health & Society > Sports, Exercise & Life Sciences
Research Centres > Centre for Health Sciences and Services
Research Centres > Centre for Physical Activity and Life Sciences

Date:

2014

Date Type:

Presentation

Event Title:

National Cancer Research Institute (NCRI) Cancer Conference

Event Dates:

02-05 November 2014

Event Location:

Liverpool, UK

Event Type:

Conference

Language:

English

Status:

Unpublished