Petros, N., Opacka-Juffry, J. and Huber, J. (2013) Psychometric and neurobiological assessment of resilience in a non-clinical sample of adults. Psychoneuroendocrinology. 38(10), pp. 2099-2108. 1873-3360 (online), 0306-4530 (print).
| Item Type: | Article |
|---|---|
| Abstract: | Background: Resilient individuals are capable of adjusting and coping successfully in the face of adversity. Efforts to assess resilience and its biomarkers have focused on individuals with a history of trauma and related disorders. Objective: To psychologically assess resilience in a non-clinical community population through questionnaires, and analyse the associations between the psychological parameters and salivary cortisol and dehydroepiandrosterone sulphate (DHEA-S) as putative biomarkers of resilience. Method: An opportunistic sample (n=196) completed a cross-sectional survey assessing resilience, self-reported depressive symptoms and anxiety, and possible correlates. A sub-sample (n=32) selected in order to maximise variation of mental health, provided saliva samples for enzyme-linked immunoassay (ELISA) detection of cortisol and DHEA-S. Conclusion: Resilience is associated with positive aspects of psychological health and salivary DHEA-S, suggesting the latter can be treated as a biomarker of resilience in a non-clinical sample of adults. |
| Uncontrolled Keywords: | Cortisol, DHEA, DHEA-S, dehydroepiandrosterone, depression, early life stress, enzyme-linked immunoassay, hypothalamic–pituitary–adrenal axis, resilience, social support |
| Subjects: |
R Medicine > RC Internal medicine > RC435 Psychiatry > RC530 Neuroses > RC537 Depression R Medicine > R Medicine (General) > R726.7 Health psychology Q Science > QP Physiology > QP351 Neurophysiology and neuropsychology |
| Creators: | Petros, Natalia, Opacka-Juffry, Jolanta and Huber, Jorg |
| Publisher: | Elsevier |
| Northamptonshire and East Midlands: | Health |
| Faculties, Divisions and Institutes: |
University Faculties, Divisions and Research Centres - OLD > Research Centre > Centre for Health and Wellbeing Research University Faculties, Divisions and Research Centres - OLD > Research Centre > Institute of Health and Wellbeing > Centre for Applied Mental Health Research Research Centres > Centre for Health Sciences and Services |
| Date: | October 2013 |
| Date Type: | Publication |
| Page Range: | pp. 2099-2108 |
| Journal or Publication Title: | Psychoneuroendocrinology |
| Volume: | 38 |
| Number: | 10 |
| Language: | English |
| DOI: | https://doi.org/10.1016/j.psyneuen.2013.03.022 |
| ISSN: | 1873-3360 (online), 0306-4530 (print) |
| Status: | Published / Disseminated |
| Related URLs: | |
| URI: | http://nectar.northampton.ac.uk/id/eprint/5356 |
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