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Creation of a large deletion mutant in Campylobacter jejuni reveals the lipooligosaccharide gene cluster is not required for viability

Marsden, G. L., Li, J., Everest, P. H., Lawson, A. J. and Ketley, J. M. (2009) Creation of a large deletion mutant in Campylobacter jejuni reveals the lipooligosaccharide gene cluster is not required for viability. Journal of Bacteriology. 191(7), pp. 2392-2399. 0021-9193.

Item Type: Article
Abstract: Deletion of the lipooligosaccharide biosynthesis region (Cj1132c to Cj1152c) from the genome of Campylobacter jejuni NCTC11168 shows that the core is not required for viability. The mutant was attenuated for growth and has increased sensitivity to antibiotics and detergents. Natural transformation and invasion of cultured host cells was abolished.
Subjects: Q Science > QR Microbiology > QR75 Bacteria
Creators: Marsden, Gemma L, Li, J, Everest, P H, Lawson, A J and Ketley, J M
Publisher: American Society for Microbiology
Faculties, Divisions and Institutes: University Faculties, Divisions and Research Centres - OLD > Faculty of Health & Society > Sports, Exercise & Life Sciences
Faculties > Faculty of Health & Society > Sports, Exercise & Life Sciences
Date: 30 January 2009
Date Type: Publication
Page Range: pp. 2392-2399
Journal or Publication Title: Journal of Bacteriology
Volume: 191
Number: 7
Language: English
DOI: https://doi.org/10.1128/JB.01397-08
ISSN: 0021-9193
Status: Published / Disseminated
Refereed: Yes
URI: http://nectar.northampton.ac.uk/id/eprint/3328

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